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uniprot.org/

UniProt REST API

Freeauth: noneCC-BY-4.0#research-grey-literature#biology#protein#api#open-data✓ verified Nov 11, 2026

UniProt REST API

UniProt (uniprot.org) provides a keyless REST API for protein sequences and curated functional annotation (UniProtKB, UniRef, UniParc), maintained by EMBL-EBI, SIB and PIR. A live UniProtKB entry query confirms the service.

Required Attribution:

Required under CC BY 4.0.

Coverage

Protein sequences and curated functional annotation (UniProtKB, UniRef, UniParc), confirmed live today via a UniProtKB entry query (accession P69905). Bulk downloads are also available via UniProt's FTP site. History start and update frequency: Not stated.

Verdict

Keyless REST API (plus FTP bulk downloads) for protein sequences and curated functional annotation (UniProtKB, UniRef, UniParc) from UniProt (EMBL-EBI, SIB, PIR). Licensed CC-BY-4.0: the FTP LICENSE file says: "We have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/) to all copyrightable parts of our databases." Rate limits: Not stated. Signal Lab links only.

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