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string-db.org/

STRING Protein-Protein Interaction API

Freeauth: noneCC-BY-4.0#research-grey-literature#biology#protein-interactions#api#open-data✓ verified Nov 11, 2026

STRING Protein-Protein Interaction API

STRING (string-db.org) provides a keyless HTTP API for known and predicted protein-protein interaction networks across many organisms, including functional enrichment analysis. A live version query confirms API version 12.5.

Required Attribution:

Required under CC BY 4.0.

Coverage

Known and predicted protein-protein interaction networks (physical and functional associations) across many organisms, with functional enrichment analysis, confirmed live today via the API version endpoint (12.5); bulk data is also available via the download page. History start and update frequency: Not stated.

Verdict

Keyless HTTP API (JSON/TSV/image) for known and predicted protein-protein interaction networks across many organisms, with functional enrichment analysis, from STRING (string-db.org, version 12.5 confirmed live today). Licensed CC-BY-4.0: "All data and download files in STRING are freely available under the Creative Commons Attribution 4.0 (CC BY 4.0) license. When using the data, please credit STRING and indicate any changes or additions you made to the data." Rate limits: the access page's "API limits" section says: "By using the Application Program Interfaces (APIs), it is possible to access STRING data without using a web browser. Please bear in mind that this mechanism should only be used for limited or occasional database access, in order to avoid overloading the server. If you need larger amounts of data (such as for example all interactions in Homo sapiens), please use the Download page instead - which is also more efficient." No numeric quota is stated. Signal Lab links only.

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