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Datasets / Research & Grey Literature
reactome.org/

Reactome Content Service API

Freeauth: noneCC0-1.0#research-grey-literature#biology#pathways#api#open-data✓ verified Nov 11, 2026

Reactome Content Service API

Reactome (reactome.org) provides a keyless REST Content Service for curated human biological pathways and reactions, with orthology-inferred pathways for other species. A live database-version query confirms version 98.

Required Attribution:

Not required for CC0 data; required for the separately licensed illustrations/art/branding materials.

Coverage

Curated human biological pathways and reactions, with orthology-inferred pathways for other species, confirmed live today via the Content Service database-version endpoint (version 98). Data is licensed CC0-1.0; Pathway Illustrations, Icon Library, Art and Branding Materials are licensed separately under CC BY 4.0. History start and update frequency: Not stated.

Verdict

Keyless REST Content Service for curated human biological pathways and reactions (with orthology-inferred pathways for other species) from Reactome (database version 98 confirmed live today). Licensed CC0-1.0 for data: "All data in the Reactome database and files derived from that data are licensed under the Creative Commons Public Domain Dedication (CC0) . User may copy, modify, and distribute these data, even for commercial purposes, without asking for permission." Pathway Illustrations, Icon Library, Art and Branding Materials are licensed separately: "This Reactome content is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0) ." Rate limits: Not stated. Signal Lab links only.

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