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rest.ensembl.org/

Ensembl REST API

Freeauth: noneCustom#research-grey-literature#biology#genomics#api#open-data✓ verified Nov 11, 2026

Ensembl REST API

Ensembl's REST API (rest.ensembl.org) provides keyless access to genome annotation for vertebrate species — genes, transcripts, sequences, variants, homology and cross-references. The disclaimer page says: "Ensembl imposes no restrictions on access to, or use of, the data provided and the software used to analyse and present it."

Required Attribution:

Not stated as a mandatory credit line on the checked pages.

Coverage

Genome annotation for vertebrate species (genes, transcripts, sequences, variants, homology, cross-references), confirmed live today via /info/ping. The same disclaimer page adds: "Some of the data and software included in the distribution may be subject to third-party constraints. Users of the data and software are solely responsible for establishing the nature of and complying with any such restrictions." History start and update frequency: Not stated.

Verdict

Keyless REST API for vertebrate genome annotation (genes, transcripts, sequences, variants, homology, cross-references) from EMBL-EBI. Licensed Custom (no-restrictions disclaimer): "Ensembl imposes no restrictions on access to, or use of, the data provided and the software used to analyse and present it." The same page adds a third-party caveat: "Some of the data and software included in the distribution may be subject to third-party constraints. Users of the data and software are solely responsible for establishing the nature of and complying with any such restrictions." Rate limits, per the Ensembl REST wiki: "we are allowed 55000 requests over an hour (3600 seconds) meaning we can perform an average of 15 requests per second". Signal Lab links only.

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